Please use this identifier to cite or link to this item: https://hdl.handle.net/10953.1/5597
Title: Consumo voluntario de ansiolíticos en ratas Wistar: Efectos de la administración intermitente.
Authors: Gaitán-Moyar, Ana.
metadata.dc.contributor.advisor: Torres-Bares, Carmen
metadata.dc.contributor.other: Universidad de Jaén. Psicología
Abstract: En este TFG, se ha analizado los patrones de consumo voluntario del clordiazepoxido (CDP}, tratando de ver el análisis de si dichos patrones podían diferir en función de que el fármaco se presentara de forma continua vs. intermitente. Exponiendo a los animales (ratas Wistar) a una prueba de preferencia. La mitad de los recibieron el fármaco todos los días (grupo CDP/C), y el resto en días alternos, en la mitad de las sesiones (grupo CDP/1). Se midió el consumo de ambas botellas y se calculó un índice de preferencia, para ver de qué botella prefería beber el animal. Los resultados indicaron que la manipulación realizada, no produjo los resultados esperados, dado que no se obtuvieron diferencias significativas entre los grupos. No se mostraba tendencia a beber CDP, ya sea porque los animales no detectaron las propiedades farmacológicas de este ansiolítico, o que dichas propiedades no fueron reforzantes.
In this TFG, it is to analyze the voluntary consumption patterns of the benzodiazepine anxiolytic chlordiazepoxide (CDP}, trying to see the analysis of whether these patterns could differ according to whether the drug was presented in a continuous vs. intermittent. Exposing the anima Is (Wistar rats) to a preference test. Half of them received the drug every day (CDP / C group}, and the rest on alternate days, in the middle of the sessions (CDP / 1 group). The consumption of both bottles was measured and a preference index was calculated to see which bottle the animal preferred to drink. The results indicated that the manipulation performed did not produce the expected results, since no significant differences were obtained between the groups. There was no tendency to drink CDP, either because the animals did not detect the pharmacological properties of this anxiolytic, or that these properties were not reinforcing.
Keywords: Clínica
Issue Date: 23-May-2017
Publisher: Jaén: Universidad de Jaén
Appears in Collections:Grado en Psicología

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